Introducing Quine: An AI research system designed for the complexity of biology

Microsoft Research launched Quine, a research system combining a multimodal world model of biology with an interactive framework connecting scientific tools, literature, and researchers. With the Broad Institute, it applied the system to pancreatic ductal adenocarcinoma (PDAC) research, predicting and ranking compounds that could drive tumor cell state transitions; wet-lab validation confirmed top-ranked candidates, and narrowing the compound pool to validation candidates took just one weekend.