Lab-in-the-Loop at Compute Speed — Ian Quigley, Leash Bio
On a podcast, Leash Bio's Ian Quigley explained how its DNA-encoded library (DEL) technology tames high-throughput protein-small-molecule interaction data and trained the Hermes model, which matches Boltz on public benchmarks using only the company's own data. The team also uncovered tens of thousands of lab-in-the-loop simulation data points, grew into Minos within two months, and today released a preprint, blog post, and open dataset for reinforcement learning where AI agents do verifiable scientific reasoning.